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Approaches to Protein Structure Prediction

Chhavi Jain


Proteins are the building blocks of virtually every cell of living organisms. They participate in various metabolic processes of the body and are required for the survival of living beings. Proteins are composed of amino acids that are linked to each other by peptide bonds. Protein molecules finally fold into specific three-dimensional structure that determines the biological function of that particular protein. Knowing the structure of protein macromolecules requires detailed investigation. Here, few approaches discussed here for determining protein structure and some of the applications associated with the approach are also mentioned.

Keywords: ab initio, homology, protein, structure, threading

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S. Selvaraj. Approaches to Protein Structure Prediction and Their Applications (

Zhiyong Zhang. An Overview of Protein Structure Prediction: From Homology to Ab Initio. Final Project For Bioc218, Computational Molecular Biology.

Jooyoung Lee, Sitao Wu, and Yang Zhang. Ab Initio Protein Structure Prediction.


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