Review on Preparation and Applications of Formazan Compounds
Abstract
The objective of the survey designated in this study is to predict the redox-active feature of formazan derivatives. To realize this purpose, preparation processes and investigation approaches of the formazan derivatives are developed. The redox properties of formazan derivatives were identified via electrochemical approaches and the first samples of isolated and well-investigated formazan products are designated in this review. Formazan derivatives (as a dyes) are synthetic chromogenic yields of the reduction of formazan via dehydrogenases with reductases. They have a variation of colors from (dark blue to deep bloodshot to orange), depending on the original formazan applied as the substrate to the reaction. Leading this sample of formazan involves several medical and pharmaceutical applications as enzymatically or through direct reaction with NADH or NADPH the classical formazan derivatives, the formazan dyes are usually used in cell proliferation and poisonousness tests like the Epi-Derm besides Epi-Skin investigations since they merely stain living, metabolically active cells.
Keywords: Formazan, azo, imine, anticancer, antimicrobial, ligand, antibacterial.
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Cite this Article: Nagham Mahmood Aljamali, Alaa Jawad Kadhim, Jalal Hasan Mohammed, Rajaa Abdulameer Ghafil. Review on Preparation and Applications of Formazan Compounds. International Journal of Thermodynamics and Chemical Kinetics. 2019; 5(2): 23–33p.
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