Anti-tubercular activity of dioxo molybdenum (VI) metal complexes of 2-((E)-(1,5-dimethyl-2-phenyl-3-((Z)-(quinoline-8-ylimino)methyl)-2,3-dihydro-1H-pyrazole-4-ylimino)methyl)phenol

Authors

  • Ashish Kumar Department of Applied Sciences, G.L. Bajaj Institute of Technology and Management, Greater Noida (U.P.)
  • Brij Kishore Tiwari Department of Applied Sciences, G.L. Bajaj Institute of Technology and Management, Greater Noida (U.P.)
  • Tasneem Sultan Department of Chemistry, Meerut College, Meerut (U.P.)
  • Anuj Kumar Sharma Department of Pharmacy, Translam institute of Pharmaceutical Education & Research, Meerut

Abstract

Dioxomolybdenum(VI) complexes tetradentate ligand 2-((E)-(1,5-dimethyl-2-phenyl-3-((Z)-(quinoline-8-ylimino)methyl)-2,3-dihydro-1H-pyrazole-4-ylimino)methyl)phenol was synthesized by conventional method The ligands and their MoO22+ complexes have been characterized on the basis of elemental analysis, electronic. I.R., 1H and 13C-NMR spectral method, by their spectral studies, octahedral geometry of the complex has been proposed. On evaluation of in-vitro antitubercular activity of the ligand and dioxo Mo(VI) metal complex found that complex is more potent antitubercular agent than ligand. Keywords: anti-tubercular agent, dioxo Mo (VI) metal complex

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Published

2020-05-26

Issue

Vol. 3 No. 1 (2017)

Section

Articles