Review of Human Genome Project (Genomic Data of Human Health)

Abstract

The Human Genome Project (HGP) has already generated findings that are influencing both basic biology study and clinical treatment. For instance, work is well on to create a genetic map of the rat, a good model for investigating complicated illnesses like hypertension, diabetes, and alcoholism. Researchers have also successfully mapped the mouse genome. In terms of the technological
obstacles that had to overcome and the numerous immediate and long-term advantages that have emerged, it is similar to the moon landing. is a significant scientific achievement. It also showed how scientists from around the world might cooperate to realize a dream that many people thought was unattainable. In terms of scope and expense, the Human Genome Initiative is unique from all earlier scientific or medical endeavors. The ability to anticipate an individual’s health or disease may have negative repercussions if the genome’s sequence were known. Another essential objective was to inform the public and experts about the HGP. Despite not being an early objective of the HGP, identifying genetic variants (gene discovery) was included not long after the HGP got underway. The number of protein-coding genes, that is currently thought to be around 19 000, was estimated more realistically by HGP. Numerous individual whole-genome sequences will be developed as DNA sequencing costs continue to decline. These DNA sequence data provide numerous opportunities for evaluating the types of human genetic variability, their connection to illness and typical dynamic capability, in addition to the knowledge the patterns can reveal about human beginnings.