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Treating the Rats Suffering from Carcinogen Induced Toxicity with Preparations from Prepupal Stages of Black Soldier Fly (BSF)

Vitthalrao Bhimasha Khyade, Apurva Baban Tamhane

Abstract


The preservative role of the methanolic maceratives of pre-pupal stages of black soldier fly, Hermetia illucens (L.) (MMPPSBSF) was assessed against the immunosuppressing and organ specific laboratory carcinogenic compound, the DMBA. Treating the individuals of Norwegian rat exerted lowering the total protein level, level of albumen and the level of globulin in the serum. There was increase in the level of urea, level of uric acid and level of creatinine in the serum of recipients of DMBA. There was increase in the activity of enzymes: AST (Asparate aminotransferase), ALT (Alanine aminotransferase) and LDH (Lactate dehydrogenase) in the serum of rat. Methanol Extractives of Pre-pupal Stages of
Black Soldier Fly (MEPSBSF) treatment in present attempt was found to cause a significant increase in the levels of total proteins, albumin and globulin in the serum. Methanol Extractives of Pre-pupal Stages of Black Soldier Fly (MEPSBSF) thus, providing protection through maintenance of level of the total proteins, albumin and globulin in the serum. Use of Methanol Extractives of Pre-pupal Stages of Black Soldier Fly (MEPSBSF) may open a new avenue to control the damages caused by the carcinogens.


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