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Review of Reactive Extraction Process for Recovery of Pyruvic Acid

Kiran D. Patil, Amruta T. Mokashi

Abstract


Pyruvic acid having a molecular formula (C3H4O3) is an important alpha-keto-carboxylic acid. It is mainly manufactured by biotechnological routes or chemical synthesis. There are number of applications of pyruvic acid in the industrial sector such as chemical, food, cosmetic and agriculture sector. The main problem for the production of pyruvic acid from the fermentation broth is downstream processing. The number of techniques developed to recover this acid from their aqueous solution such as ion exchange chromatography, sorption, pervaporation, membrane process, liquid-liquid extraction etc. Reactive extraction is novel energy efficient technology used for recovery of acid from fermentation broth as well as from aqueous solution. This review article presents the recent developments for the recovery of pyruvic acid by reactive extraction. The main aim of this study is to discuss the efficiency of reactive extraction process in recovery of pyruvic acid from aqueous solutions using different extractants and diluents. The development in extractants and diluents makes the study very economical and specific. Equilibrium study take place to compare the extractants and diluents used for the separation in terms of distribution coefficient and extraction efficiency. In this work, comparison study of the effect of various parameters such as initial acid and extractant concentration, pH of an aqueous phase, the temperature of the system, phase volume ratio, type of microorganism used and toxicity of solvent has been carried out. In addition to this, the various kinetics and modelling parameters such as stirring speed, an order of reaction, a rate constant, a mathematical model (e.g. LSER) is also compared. Keywords: Diluents, extractants, fermentation, pyruvic acid, reactive extraction

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References


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